This study was carried out to investigate the effects of light intensity and growing media on the growth and yield of Solanecio biafrae. It was a factorial experiment which involved using three light regimes which include; half shade (HS; 600 flux), more intense shade (MIS; 63.6 flux), and full light (FL; 1120 flux), and four growing media; rice husk + cocopeat (M1), rice husk (M2), biochar (M3), and topsoil (M4). Light intensity significantly influenced performance in which HS produced the highest leaf production (23.38), MIS induced greater stem elongation (35.31 cm) but reduced biomass, while FL resulted in the lowest leaf number and height (20.88 and 20.69) Growing media effects were also observed where biochar (M3) and rice husk + cocopeat (M1) enhanced leaf number height, and fresh weight, rice husk (M2) and topsoil (M4) performed less. A strong interaction between light and medium was observed, with HS × biochar and HS × M1 performing better in terms of growth and yield, while MIS × topsoil performed less. Overall, S. biafrae performed optimally under moderate shade combined with nutrient-rich organic substrates; this is consistent with its natural adaptation to shaded plantation environments. These findings provide a basis for sustainable domestication and improved cultivation of this underutilized vegetable.