The integration of sustainable plant products into aquafeeds has emerged as a crucial strategy for addressing the environmental and economic challenges facing the aquaculture industry. This comprehensive review examines the opportunities and challenges associated with incorporating plant-based ingredients in aquafeed formulations. We discuss the advantages of plant-based ingredients, key considerations in feed formulation, innovations in plant-based aquafeeds, and the importance of meeting nutritional requirements and optimizing feed performance. By exploring the latest advancements and future directions in sustainable aquafeed development, this review highlights the potential of plant-based ingredients to enhance feed sustainability, improve fish health and performance, and promote responsible aquaculture practices on a global scale.